Do I need to apply to the IBC if I am working with biohazardous materials but not with recombinant DNA?

Yes.  The GS IBC reviews and approves all research involving biohazardous materials, as defined below. IBC registration and approval of research involving these biohazards is required.

• Naturally occurring or engineered micro-organisms or viruses capable of causing disease in humans and/or animals. These are Risk Group (RG) 2, 3 or 4 pathogens as defined by NIH (Note: this list is not all inclusive). Those agents not listed in RG 2, 3, and 4 are not automatically or implicitly classified as non-pathogens or in the Risk Group
• A risk assessment must be conducted based on the known and potential properties of the agents and their relationship to agents that are listed. Consult the following web sites for guidance.
  • NIH  – Biodefense and Select Agents 
  • CDC  – Federal Select Agent Program
• Human or mammalian cell lines (including embryonic & established), human tissue or blood.
• Toxins derived from plants, animals or micro-organisms that will have adverse effects in humans or animals.
• Plant pathogens or pests (arthropods, nematodes, weeds) that are regulated by state or federal policy or law. Consult the following web sites for up to date lists of regulated organisms.
  • USDA/APHIS – http://www.aphis.usda.gov/ppq/regpestlist
• Select biological agents that may adversely affect public health, animal or plant health, or animal or plant products. Note: all possession and use of Select biological agents requires special registration through the Biological Safety Officer.
  • CDC program – http://www.cdc.gov/od/sap/index.htm

Last updated: 7/5/2023